Full Time

CSO/CTO/Biotechnology Founding Partner – RNA Delivery System

Posted 4 weeks ago
Application ends: June 29, 2023
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Job Description

Company Description Founded in 2001 and headquartered in Guangdong, China, Fapon Group is mainly engaged in product R&D and services of in vitro diagnostic (IVD), biological therapy, and precise diagnosis and treatment. With our core value of “foresee and prepare for what future demands”, Fapon focuses on three major businesses: raw material solutions, IVD ecosystem platform service, and intelligent digital diagnosis and treatment. Based on the global industrial ecology, Fapon has established major production and sales (R&D) bases in Beijing, Shenzhen, Shanghai, the United States, India, Singapore, and other locations throughout the world, forming a global R&D, production, marketing, and service network, with products being widely sold to 61 countries and regions. Also, Fapon has R&D bases in Boston, California, and Germany. In the field of IVD core raw material, Fapon is the leading producer in China, South Korea, India, and Brazil. Besides IVD products, Fapon also has an 8-year-old pharmaceutical division, mainly focusing on monoclonal antibody and cellular therapeutics. Its first product, a differentiated CD47 antibody, has received FDA IND approval in Feb 2023 and will start clinical trial soon. It is an important part of Fapon’s plan to enter the CGT field and develop medicines for the benefits of human beings. You can learn more about us by visiting https://en.faponbiotech.com Job Description This strategic position can be located in anywhere in the United States, Germany, or China). Fapon Group is a leading organization founded in 2001, headquartered in Guangdong, engaged in product development and services for in vitro diagnostics, innovative biopharmaceuticals, and therapeutics, and precision diagnosis and treatment. With core values of “pre-practicing the future,” Fapon has established itself as a global leader in IVD core raw material, IVD instruments and product development solutions, therapeutics, and AI/data science. Fapon has developed more than 1300 products and holds more than 500 global patents/patents under application. With a global R&D, production, marketing, and service network, Fapon has established major production and sales bases worldwide, with products exported to 45 countries and regions overseas. We are looking for a CSO/CTO/Biotechnology Founding Partner depending on the level of the candidate’s overall background with a proven track record in biochemical engineering and nanomedicine to lead the development of novel delivery systems for different technology platforms, including mRNA vaccines, therapeutics, siRNA, and in vivo gene editing. As a CSO/CTO/founding partner, you will be responsible for leading a team of experts and technicians to develop a differentiated LNP-based delivery system for RNA. Responsibilities Lead a team of experts and technicians to develop a differentiated LNP-based delivery system for RNA Collaborate with the RNA team to conduct in vitro and in vivo studies, leading to eventual clinical trials Improve upon the current mainstream LNP-based delivery systems, to increase the expression rate, lower the immunogenicity, etc. Lead formulation development of mRNA drug targets entailing delivery formulations for in vitro/in vivo studies Evaluate novel ideas for RNA delivery systems, including LNP-based systems and non-LNP-based systems Develop LNP novel formulations and explore new processes for formulation design, CMC, and large-scale production Prepare technical reports and presentations for clear communication of scientific findings across interdisciplinary teams Qualifications Minimum Qualifications : PhD in Chemistry, Physical Chemistry, Chemical Engineering, or Pharmaceutical Sciences 4 years of industry experience in RNA delivery system R&D with hands-on experience in RNA delivery system development, experience with LNP or other nanoparticles is essential Demonstrated success in nucleic acid delivery system development with hands-on experience in delivery formulations and characterization Direct experience with RNA encapsulation, quantification, and characterization Experience in developing novel and effective RNA delivery systems, which are differentiated from mainstream LNP delivery systems would be advantageous Track record of innovative and impactful research including peer-reviewed publications, expertise preferred in vaccine biology, nanoparticle formulation, oval delivery system, targeted therapy using nanoparticle Ready to work in a biotech start-up with a founding-partner mindset Ability to effectively interact and communicate with multidisciplinary scientists, both internally and externally, excellent communication, interpersonal, and presentation skills essential Preferred qualifications : Demonstrated ability to build and manage a research team Desire to work in a fast-paced environment dynamic startup environment on cross-functional teams An excellent industry network Willing to Relocate to Boston or Munich is preferred but not necessary Experience with mRNA vaccine development is preferred but not necessary Additional Information What We Offer: At Fapon US, you can have a good job that can grow into a great career. We offer: Financial security through competitive compensation, incentives, and retirement plan Health care and well-being programs including competitive medical, dental, vision & medical benefits Generous paid time off including vacation, sick time, holidays 401(k) retirement savings with a generous company match Other comprehensive voluntary benefits include but are not limited to pet insurance, life insurance, employee assistance program (EAP), discount programs, and many more The stability of a company with a record of strong financial performance year over year Collaborative and supportive work environment An equal opportunity employer, Fapon welcomes and encourages diversity in our workforce.